DESIGN OF FILL AND FINISH FACILITY FOR ACTIVE PHARMACEUTICAL INGREDIENTS (API)

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According to World Health Organization (WHO), Active Pharmaceutical
Ingredients (API) is any substance or mixture of substances intended to be used in
the manufacture of a pharmaceutical dosage form and that, when used so,
becomes an active ingredient of that pharmaceutical dosage form. The substances
are intended to furnish pharmacological activity or other direct effect in the
diagnosis, cure, mitigation, treatment or prevention of disease or to affect the
structure and function of the body [1]. There are two classifications of API which
are inorganic substances or organic substances that isolated from materials of
animal or human origin and synthetic or semi-synthetic or isolated from herbal
sources or microorganisms.

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